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Ancient Philosophers Explain 4 Ways To Be Highly Productive

“It is not that we have so little time but that we lose so much. … The life we receive is not short but we make it so; we are not ill provided but use what we have wastefully.” ~ Seneca, On the Shortness of Life

Unlikely though it may seem, some ancient philosophers have plenty to teach about time management and productivity. Perhaps the most cited class of Greek and Roman philosophers, the Stoics, spoke and often wrote about fulfilling one’s potential – to do so, of course, requires action.

What is stoicism?

Stoicism is a particular school of Hellenistic philosophy, founded in Athens around the early 3rd century BC. Among the most famous group of Stoics includes Epictetus, Marcus Aurelius, and Seneca.

Stoicism is widely practiced today; those who adhere to its teachings say that it’s a lifestyle. Despite the volumes of stoicism literature, the philosophy can be narrowed down to five central themes:

1. The world is both unpredictable and temporary.
2. As such, it is important to be steadfast, strong, and exercise self-control.
3. The root of much dissatisfaction lies in our impulsive habits.
4. Excessive craving (of money, possessions, etc.) is spiritually and morally bankrupt.
5. To live with compassion, restraint, and humility is deserving of the highest honor.

How is stoicism relevant to productivity?

Stoics preach the importance of an action mindset; and against overthinking, which often leads to ‘paralysis by analysis,’ or forgoing necessary action in favor of overthinking.

Stoic philosophy also stresses the importance of ignoring worthless distractions – something that, in today’s information age, is exceptionally rare. Indeed, attention is becoming a scarce individual commodity. The good news is that the more you cultivate this precious skill, the more prominent an advantage you will have in a competitive world.

4 Ways to Boost Productivity

Here are four Stoic ways of living that can help boost your productivity:

1. Value your time more than money

Stoics were not materialists; they were very simple-living folks who valued knowledge and a life well-lived. They were also supremely pragmatic about time – something that is all too often wasted. Here’s the Roman philosopher, Seneca, on the subject:

“No person hands out their money to passers-by, but to how many do each of us hand out our lives! We’re tight-fisted with property and money, yet think too little of wasting time, the only thing about which we should all be the toughest misers.”

Fast-forward to today; research shows that having more time correlates highly with individual happiness. On the flip side, accumulating money beyond that needed for necessities does not.

what money can't buy

2. Managing emotions is critical

Managing your time, in the Stoics view, is nothing more than controlling your emotions. Intriguingly, this perspective helped spawn emotional management systems, such as Cognitive Behavioral Therapy (CBT).

Your mood directly impacts how much you accomplish. When we’re in a negative state, we are much more likely to procrastinate than if we are neutral or positive. But when we take action, this resistance quickly dissipates.

3. “First thing’s first.”

To the Stoic mind, doing something besides what is most important is foolhardy and wasteful. Here’s the Roman emperor, Marcus Aurelius:

“It is essential to for you to remember that the attention you give to any action should be in due proportion to its worth, for then you won’t tire and give up, if you aren’t busying yourself with lesser things beyond what should be allowed…

Since the vast majority of our words and actions are unnecessary, corralling them will create an abundance of leisure and tranquility. As a result, we shouldn’t forget at each moment to ask, “is this one of the unnecessary things?”

In other words, being disciplined with our time creates even more time to do the things we enjoy. Furthermore, not all things are worth the same amount of time and attention.

4. Focus on the process

While it’s nice to visualize a good outcome, execution makes it possible. When we focus on the process instead of the result, the odds of achieving a favorable result increase drastically.

Besides focusing on the process, it is just as essential to pay attention to what can be controlled while ignoring what can’t. Here’s the Greek philosopher, Epictetus:

“Some things are in our control and others not. Things in our control are opinion, pursuit, desire, aversion, and, in a word, whatever are our own actions. Things not in our control are body, property, reputation, command, and, in one word, whatever are not our own actions.”

Final Thoughts

Today, there are a countless number of productivity tools: apps, books, calendars, planners, etc. What’s ironic is that many of these things claiming to “boost productivity” have the exact opposite effects.

Sometimes, it’s best to keep things simple. To this end, the ancient philosophers mentioned above can teach us much about life.

Sources:
http://time.com/5039919/productivity-advice-stoics/
https://dailystoic.com/what-is-stoicism-a-definition-3-stoic-exercises-to-get-you-started/
https://www.goodreads.com/author/quotes/4918776.Seneca
https://www.psychologytoday.com/blog/creativityrulz/200909/time-is-more-valuable-money

Dermatologists Reveal 10 Things To Never Put On Your Face

Did you know that the cosmetic industry is highly unregulated? The Food and Drug Administration (FDA) does not require skincare products to be approved before becoming available on the consumer market.

You read that correctly. Apparently, the regulatory agency responsible for protecting the health of nearly 400 million people does not consider it worthwhile to examine products designed specifically for the largest, most porous organ of the human body.

Good call, FDA.

Since the “Forget Dermatology Agency” doesn’t want to do its job, dermatologists say there are ten products to avoid putting on your skin and face.

10 Products To Never Put On Your Face

face

1. Physical exfoliants

“I find that both for myself and my patients, physical exfoliation can lead to irritation and dryness, especially in colder months,” explains Meghan O’Brien, MD, a dermatologist at Tribeca Park Dermatology in New York City. Using abrasive pads or wipes “can also irritate skin conditions such as acne and eczema,” adds O’Brien.

2. Mineral oil

Dendy Engelman, MD, of Manhattan Dermatology and Cosmetic Surgery in New York City, says: “Mineral oil can clog pores. This can lead to acneiform eruptions (acne resembling deep skin lesions), blackheads, milia (small skin cysts) – very undesirable results.”

Commonly used mineral oils include liquid paraffin, liquid petroleum, paraffin oil, paraffinum liquidum, petrolatum liquid, petroleum oil, white mineral oil, and white oil.

3. Regular soap

Dermatologists aren’t big fans of “old school” bar soaps. “I never, ever use a harsh, regular soap as a face or body cleanser,” says Ellen Marmur, MD, associate clinical professor in the department of dermatology at Mount Sinai Medical Center. Dr. Marmur explains that regular soap strips the skin of essential nutrients; uses harsh, unnatural chemicals, and deprives the skin of essential moisture, “leaving it rough, dry, and itchy.”

4. Fragrances

The majority of skin-care products contain some form of artificial fragrance. The problem is these fragrances often lead to breakouts and skin irritation. Furthermore, the Environmental Working Group (EWG) links fragrance mixes with allergies, dermatitis, reproductive problems, and respiratory distress.

Bear in mind that the word “fragrance” is often used to mask (no pun intended) a brand’s proprietary formula. It can be found in many products such as body wash, cologne, conditioner, moisturizers, and perfume.

5. Coarse Face Scrubs

“There is no reason to use abrasive face scrubs,” says Brooke Jackson, MD, Founder and Medical Director of Skin Wellness Dermatology Associates in Durham, North Carolina. “Most people who try them are acne patients, and you don’t scrub acne away.”

To avoid skin irritation, Dr. Jackson recommends using a cream-textured wash; using the hands to wash the face and a washcloth to dry off.

things to never put on your face

6. Self-microneedling Devices

Dr. Ava Shamban, a Beverly Hills-based dermatologist and author of Heal Your Skin, says, “I feel there’s so much risk of infection from these devices because they create all those tiny holes in the skin.”

These tiny, unnatural holes disrupt the skin’s natural foundation, says Shamban, who recommends expert-administered microneedling. “We do microneedling with radio frequency, but … in a controlled, cleaner environment, so it is safer.”

7. Home Chemical Peel Kits

At-home chemical peeling kits may seem like an expeditious and inexpensive way to achieve flawless skin. But they do carry some significant risks. Scarring of the skin, blistering, swelling and allergic reactions are good reasons to consult with a dermatologist beforehand.

Experts note that “skin sags, bulges, and more severe wrinkles” do not respond well to chemical peeling. WebMD recommends seeking the counsel of a dermatologic surgeon to determine the appropriate type of treatment for these cases.

8. Injected, permanent fillers

Looking at you, Botox. While certainly not the only substance used for injection, Botox is “the most acutely poisonous substance known to man,” according to authors at the University of Warwick.

9. Alcohol-based skin products

Here’s another good reason to read the label: alcohol, when absorbed by the skin, not only dries and irritates it; but may cause skin conditions such as acne, eczema, and rosacea.

Dr. Gervaise Gersstner, the owner of a dermatologic practice in New York City, says “Instead of alcohol, look for an essence or toner that is water based, so you’re not drying your skin out.”

10. Shampoo

Let’s clear something up ASAP: shampoo is okay to use – on your head. “I find that (people) are using shampoo in emergencies when they don’t have their regular cleansers, but shampoo is designed to clean your hair, not your skin,” says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City.

Shampoo cleaners contain surfactants that satisfactorily remove dirt, oil, and skin from your hair, but are too harsh to be absorbed by the skin.

Sources:
https://theboar.org/2014/02/botox-worlds-deadliest-poison/
http://www.health.com/beauty/coinage-dermatologists-skin-care-waste-money
https://www.huffingtonpost.com/vanessa-cunningham/dangerous-beauty-products_b_4168587.html
https://www.prevention.com/beauty/worst-beauty-products-your-skin
https://www.webmd.com/beauty/cosmetic-procedures-chemical-peel-treatments#1

Experts Explain 7 Things to Do If Your Partner Loses Their Job

“The enormous interest in the media on coping with unemployment reflects not only our recognition that missions of people are out of work and will continue to be unemployed, but that unemployment can be psychologically devastating.” ~ Robert L. Leahy, Ph.D.

Here is a question to get us started: What do you think the impact is, if any, of unemployment on a couple’s relationship?

We would think that unemployment would lead to more relationship conflict, but we’d be wrong. According to a widely-cited study, “there was no direct relationship between unemployment and marital dissatisfaction.” Some marriages even get stronger.

The ‘X’ factor is usually how the newly unemployed handles the situation. Per a study published by the National Institutes of Health, “symptoms of somatization, depression, and anxiety were significantly greater in the unemployed than employed.” The research continues goes on to explain that how a person copes with unemployment is highly variable; and that his or her actions and attitudes ultimately predict how the situation affects the partnership.

In this article, we’re going to discuss seven ways to better emotionally handle a partner’s unemployment.

Here are those 7 ways to emotionally deal with your partner losing their job:

1. Discuss and validate

Most unemployed people feel guilty and ashamed of their situation. They may believe that others look down on them or think of them as a burden. Gently opening up an avenue for discussion may help. It is important to understand that the person’s first few days or unemployment usually are when they’re the most emotionally volatile. Leave the conversation open by saying something simple like “I know this is a difficult time. I’m here for you if you need to talk.”

2. Don’t express overt pity

Yes, you ache for your partner’s situation – and rightly so. But there is a profound difference between compassion and expressing sorrow or pity. By all means, be there for them when they need to talk. If they need a shoulder to cry on, offer them yours. Just don’t invite a pity party.

3. Be tactful

If we’re completely honest, we know that periods of unemployment may create resentment between couples. Laurel Steinberg, a New York-based marriage therapist, explains “Work equals earnings, and earnings equal helping to support a family.” If a sense of resentment is growing, express your concerns tactfully and intelligently.

fix problems quote

4. Allow for a period of grief

Any significant loss, personal or professional, may provoke an episode of melancholy. “Losses can be devastating,” says Sarah Griffin, a licensed mental health counselor in Everett, Washington, “and being laid off is a primary loss.” The first couple of weeks following a job loss often involves a period of adjustment, which may or may not include grief. If it does, it is important to allow them a bit of time and space.

5. Pay attention to their mood

As mentioned, people handle crises differently – and unemployment is no exception. Many studies have found a causal relationship between unemployment and the onset of anxiety and depression. Even if you think that you “know” your partner, it remains a wise move to observe their mood states. Usually, if they’re not displaying mood swings or becoming overly sullen, things will be okay.

6. Help solve the problem (when you can)

Eventually, the problem of unemployment requires a solution. The person must realize that, as their partner, you have an obligation to help solve problems. While they may initially become angry or defensive, these feelings will subside. If you need help thinking of something to say, here’s an example: “I know that times are tough right now. You’re only human. But I’m willing to help brainstorm and come up with some strategies. Let me know if you think this would be helpful.”

7. Put things in perspective

Statistics show that upwards of 30% of people employed today were unemployed at some point in the past three years. Things happen – a weak economy, bad management, tough luck, human error – and so on. But unemployment is not the end of the world. One man who found himself out of work “realized in talking about (it) that he had a terrific wife, kids who loved him, savings, job skills, and a desire to work.” While discussing the obstacles he had overcome, he said, “You know, I have overcome worse things before.”

In closing, it’s vital to keep in mind that this is a hard time for your partner. As their significant other, you must step up and show that you’re willing to do whatever it takes to help. Remember that many relationship problems come from a diminished sense of self-worth – and some words of encouragement may be all that is needed!

https://youtu.be/tHMUnm-vDNk

(C)Power of Positivity, LLC. All rights reserved
Sources:
http://www.chicagotribune.com/lifestyles/sc-partner-underemployment-family-0920-20160916-story.html
http://www.foryourmarriage.org/when-unemployment-hits-home-seven-ways-to-help-your-marriage/
https://www.psychologytoday.com/blog/anxiety-files/201008/how-support-someone-who-is-unemployed-seven-steps-making-difference

8 Things Assertive People Do Differently In Their Relationship

Assertiveness is the quality of being self-assured and confident without being aggressive. In the field of psychology and psychotherapy, it is a learnable skill and mode of communication. ~ Wikipedia

Please reread the above definition, but this time try to list as many of the keywords or phrases that you find. Write them down.

Got it? Okay, so here they are:

  • ‘Quality’ – in this respect, a personality trait.
  • ‘Self-assured and confident’ – understanding your worth and portraying a poised attitude.
  • ‘Without being aggressive’ – assertiveness is not aggressiveness – it is relaxed and thoughtful; not forceful or brash.
  • ‘A learnable skill’ – Assertiveness is a trait that can be developed.
  • ‘Mode of communication’ – Assertiveness is evident through both verbal and non-verbal means of communicating.

Why Being Assertive Is Crucial

Now that we have a contextual understanding of assertiveness, let’s talk about its role in our lives.

We’ll all concede that the world is full of problems. Should you feel the need to convince yourself, flip on the local news and watch for five minutes! It helps to have a disposition of assertiveness when things get hairy.

We all experience good, bad, and neutral relationships. Many have had someone (many times, a trusted someone) betray, harm, or unjustly oppose them.

The relationship dynamic of human beings has been illustrated using a summarized version of ‘The Parable of the Sheep,’ which involves three characters:

  • The Wolves: Default mode is aggression and violence; they prey on the sheep. They act without a conscience.
  • Sheep: Innocent and loving; yet at times meek and passive. They are targets of the wolves.
  • Sheepdogs: Also benevolent and loving, yet have the capacity for swift action. Sheepdogs protect themselves, the sheep, and stand up to the wolves.

What differentiates sheepdogs from wolves is their concern for the welfare and safety of others; acting with a purpose and with intelligence, and having a healthy mindset. Should the need arise, the sheepdog will act swiftly and definitively, though it is neither their default or preferred state of being.

In this story, the sheepdog is an ideal example of assertive behavior.

“That’s great,” you may think, “but how does this apply to me?” Well, although this article focuses on assertiveness and relationships, it is relevant to many areas of your life, including:

  • Work: doing what needs to be done.
  • Home life: taking care of family, friends, and responsibilities.
  • Self-discipline: being persistent and not acting whimsically.
  • Goal achievement: having a purpose and a plan for life.

Relationships and Assertiveness

Relationship-wise, assertiveness is acting in a manner appropriate for the person and situation. In relationships, the assertive person:

  • is respectful at all times
  • communicates directly, honestly and openly
  • tactfully says what needs to be said
  • humbly explains what they need or want
  • acts in an honorable, virtuous manner

As stated, assertiveness is a learned trait.

In the context of relationships, here are eight things assertive people do differently:

1. They know their intention

Before you initiate a discussion or raise an issue, your intention should be well understood. When you engage in a semi-serious talk without having a plan (the requisite knowledge, how to present ideas, etc.), you risk losing the attention of the person on the other end. A lack of intention is a lack of assertiveness.

2. They pick their battles

In any relationship, personal or professional, it is essential to pick your battles. In other words, we must forgo the need to be right (even if we are) unless the matter is of a critical nature. One right way to pick your battles is to keep your eye on the prize; whether it’s a promotion, loving relationship, peace of mind or something else.

3. They use empathy

Empathy is the ability to put yourself in someone else’s shoes. Assertive communication occurs when you treat the other as an equal, not less than or better than yourself. If necessary, to get into this state of mind, try practicing self-compassion (meditation is an excellent way of doing this!)

assertive relationship

4. They do not sacrifice their values

When it comes to relationships, do you have a set of values by which you abide? These individual values (or virtues) are compelling because you and only you are responsible for their implementation. Respect, equality, honesty, dignity, and other core values should be adhered to in every interaction – good or bad.

5. They are active listeners

It does no good to communicate with assertiveness only to tune out when someone else has their say. Active listening, whether in a personal or professional setting, demands three things: complete attention to the speaker, not interrupting, and asking questions when something is unclear.

6. They finish unfinished business

Assertive communicators don’t rehash mistakes and errors of the distant past during conversation. If the past repeatedly surfaces mid-convo, it is a definite sign that a resolution to the problem was never attained. Address all unfinished situations; then approach the conversation from a ‘From now on’ mindset.

7. A strong sense of commitment

While this may seem commonsensical, many people stumble over the commitment aspect of conversations, conflict resolution, and relationships. Without an attitude of commitment, little will change. An assertive mindset requires a steadfast assurance from both parties and a positive mindset.

8. They say “Please” and “Thank you.”

Courtesy is a powerful relationship builder. Assertive individuals, while inherently polite and well-mannered, are also smart enough to understand those simple niceties can only benefit them and their relationships. Yes, this includes saying “Thank you” upon the conclusion of a dialogue where things don’t entirely go your way.

Stay assertive!

5 Ways To Spot A Compulsive Liar And Break Free From Them

Have you ever met someone whose every word needed to be taken with a grain of salt? How about someone whose stories seem to always convey a sense of exaggeration? If so, you may have known a compulsive liar.

Compulsive lying, also known as pathological lying (PL), describes someone with a history of habitual lying for “which no apparent psychological motive or external benefit can be discerned.” Many experts claim that PL can become a hardwired behavior – an addiction to lying.

Few people demonstrate an aptitude for compulsive lying quite like Patrick Couwenberg, a former Superior Court Judge of California.

In 2001, Couwenberg was removed from his position “by the state judicial commission after it concluded that he repeatedly lied about being a Caltech graduate, a wounded war veteran and a CIA operative in Laos in the 1960’s.” “This is a true tragedy,” said Edward P. George, the judge’s attorney. Apparently, compulsive lying is a thing among lawyers. Shocking, we know!

The lessons from the “Judge” Couwenberg case:

– Compulsive liars are everywhere.
– Some compulsive liars are skillful at deception.
– The act of compulsive lying may directly or indirectly harm others.

On an individual level, it certainly behooves us to (a) have the ability to single out compulsive liars, and (b) take the proper actions.

Without further delay, here are 5 ways to spot a compulsive liar:

1. They are professional manipulators

Make no mistake about it: many (most?) compulsive liars are professional schemers. They engage in espionage, of sorts. They will know everything to say and do. Because of this observation, they know what you want or don’t, and will “study” your behavior and mannerisms. They may even use emotional or sexual arousal to achieve their aims. They also use psychological tactics, like piquing your interest, and emotional tactics, like conveying a sense of empathy, to attract or distract you.

Taking action: Should you feel that the person you’re dealing with is a compulsive liar, attentively listen to their words. Do they convey a sense of knowing too much about you? Do they track your movements or act overtly emotional or sexual? If so, avoid them.

2. They have no reservations about lying

Compulsive liars are similar to narcissists in that they both lack empathy for others. Its typical for someone with narcissistic traits to compulsively lie, and vice-versa. They don’t care about your feelings, nor do they care how their mistruths will affect your life. Remember, compulsive lying is impulsive lying – and impulses don’t discriminate.

Taking action: Pay attention to the potential liar’s way of communicating with others. Can you spot a pattern of improper behavior? If they act disrespectful or unconcerned towards you or others, consider separating yourself as much as possible.

how to spot a compulsive liar

3. They’re always trying to impress

Compulsive liars have a proclivity for exaggerating things. Oftentimes, their stories are crafted to present themselves in a highly desirable way. Similar to the fake judge, a compulsive liar often “decorates their own person” by telling stories that present themselves as the hero or the victim. They may share stories about personal acts of bravery, how they know influential people, or how much power or wealth they have.

Taking action: Don’t bother calling their bluff. This won’t do you any good, and may even make you a possible target. Ignore and separate.

4. They show no reaction when lying

Normal people will feel anxious or guilty when lying about things. On the other hand, compulsive liars do not share the same sentiment. Furthermore, they will consciously avoid doing the things that others do when lying, like touching their face, shifting their body, or avoiding eye contact. Instead, they’ll smile, act laid-back, and use some humor to throw you off.

Taking action: Action here requires recalling if and when the person lied to you, or if a trusted confidant conveys their experience. “He lied like it was no big deal,” or “she looked me straight in the eye and lied” – or some variation of these phrases are something to watch for.

5. They show other personality traits

Psychologists state that pathological lying is more common for people with certain personality traits, including:

– Narcissism or self-centered behaviors and thought patterns
– Selfishness
– Abusive attitude
– Obsessive, controlling, and compulsive behaviors
– Impulsivity
– Aggressiveness
– Jealous behavior
– Manipulative behaviors
– Deceptiveness
– Socially awkward, uncomfortable, or isolated
– Low self-esteem
– Temperamentalness
– Anger

Taking action: It is almost always better if you can take concrete steps to avoid compulsive liars. However, this preemptive maneuvering may not always be possible. In the workplace, should the individual convey anger or aggression towards you or someone else, report it. If you must do so, explain that you wish for the report to remain confidential.

In a personal setting, evaluate your options and the degree of severity. The actions you take may range from removing yourself from the situation to calling the police. Use your best judgment.

(C)Power of Positivity, LLC. All rights reserved

Science Explains Why Coffee Drinkers Live Longer

Good news, coffee addicts everywhere – that cup of joe you drink every morning before work doesn’t just wake you up; it may help increase your lifespan, too!

In a groundbreaking study, researchers have found a link between an inflammatory process and the development of cardiovascular disease later in life. Enter caffeine. Researchers found that caffeine consumption could combat this inflammation.

Lead author David Furman, Ph.D., of the Institute for Immunity, Transplantation and Infection at Stanford University in California, and colleagues published their study in the journal Nature Medicine.

“That something many people drink – and actually like to drink – might have a direct benefit came as a surprise to us. We didn’t give some of the mice coffee and the others decaf. What we’ve shown is a correlation between caffeine consumption and longevity. And we’ve shown more rigorously, in laboratory tests, a very plausible mechanism for why this might be so.” – Mark Davis, Ph.D.

Many people turn to coffee to get them through each day, but it turns out that coffee can provide many more benefits than just keeping us awake. Several studies have already pointed out the health benefits of drinking coffee. One study, for example, discovered that people who drank one to five cups of coffee per day had a lower risk of all-cause mortality than their coffee-abstaining counterparts.

However, these previous studies did not pinpoint why coffee drinkers actually live longer. Furman and his colleagues have found the association at last.

Scientists Explain Why Coffee Drinkers Live Longer

The study

To begin with, Furman and his team wanted to figure out the exact inflammatory processes that cause heart problems later in life.

The team analyzed data from two groups of people: one group of healthy adults between ages 20 and 30, and one group of healthy adults 60 and older.

They assessed blood samples from the participants and identified two gene clusters that were more highly activated in the second group. They discovered that these gene clusters were linked to the production of IL-1-beta, a type of circulating inflammatory protein.

Next, the team took 23 older subjects and placed them into one of two groups based on their activity levels in one or both gene clusters.

Then, the research team analyzed the participants’ medical history. Among the 12 subjects with high gene cluster activity, nine had high blood pressure, compared with only one of the 11 participants with low gene cluster activity.

They also discovered that the older participants with high gene cluster activity had a significantly higher probability of having arterial stiffness – a risk factor for heart attack and stroke – compared with the low gene activity subjects.

Furthermore, the researchers found that subjects in the high gene cluster activity group who were 85 or older in 2008 were significantly more likely to have passed away by 2016.

Adults in the high gene cluster activity group also had high concentrations of IL-1-beta in their blood, as well as more free radicals – which can contribute to the growth of cancer – and a number of nucleic acid metabolites which are produced by free radical activity.

After confirming the link between these gene clusters and inflammation, the researchers were able to increase activity in one of the gene clusters by incubating an immune cell with two of the nucleic acid metabolites produced by free radical activity. This resulted in an increase in IL-1-beta production.

coffee

The team then injected mice with these metabolites, and found that they suffered from high blood pressure and systemic inflammation. Furthermore, the renal pressure of the mice increased because of the impacted immune cells, which blocked their kidneys. Researchers found that caffeine consumption might combat the negative impacts of these metabolites.

After looking at the participants’ caffeine intake, the researchers found that the blood of older adults with low gene cluster activity was more likely to contain caffeine metabolites, such as theophylline and theobromine.

When the researchers incubated immune cells with the caffeine metabolites and the nucleic acid metabolites, they discovered that the caffeine metabolites prevented the inflammatory effects of the nucleic acid metabolites.

Co-senior author Mark Davis, Ph.D., also of the Institute for Immunity, Transplantation and Infection at Stanford, says these discoveries show that “an underlying inflammatory process, which is associated with aging, is not only driving cardiovascular disease but is, in turn, driven by molecular events that we may be able to target and combat.”

(C)Power of Positivity, LLC. All rights reserved
Sources:
https://www.medicalnewstoday.com/articles/315300.php
http://circ.ahajournals.org/content/early/2015/11/10/CIRCULATIONAHA.115.017341
https://www.nature.com/articles/nm.4267
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